Orofacial motor dysfunction in Moebius syndrome

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Moebius syndrome

Moebius syndrome is a rare, nonprogressive neurological disorder (prevalence is estimated to be 0.002% of births) characterized by unilateral or bilateral facial paralysis and defective extraocular eye movements secondary to congenital paresis of the facial (VII) and abducens (VI) cranial nerves. These classic features of the syndrome are often accompanied by hypoglossal (XII), trigeminal (V), ...

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Moebius syndrome.

Moebius syndrome consists of congenital complete or partial facial nerve palsy with or without paralysis of other cranial nerves (most commonly an abducens paralysis) and often associated with other malformations of the limbs and orofacial structures. The first description of congenital facial diplegia was given by von Graaefe in 18801 and this was soon followed by other reports. Moebius2 3 dre...

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The Temporomandibular Joint Pain Dysfunction Syndrome and The Orofacial Pain

Headache and orofacial pain due to the temporomandibular joint {TMJ) pain dysfunction syndrome is a cause of human suffering often resulting from major diagnostic and therapeutic difficulties. These difficulties arise from the fact that the syndrome is rather little known among dentists as well as other medical specialists. The main symptom of the dysfunction syndrome is pain, on account of whi...

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Apraxia and Motor Dysfunction in Corticobasal Syndrome

BACKGROUND Corticobasal syndrome (CBS) is characterized by multifaceted motor system dysfunction and cognitive disturbance; distinctive clinical features include limb apraxia and visuospatial dysfunction. Transcranial magnetic stimulation (TMS) has been used to study motor system dysfunction in CBS, but the relationship of TMS parameters to clinical features has not been studied. The present st...

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Moebius syndrome . Deletion of chromosome 13 in

A girl aged 21⁄2/ years with Moebius syndrome was found to have a deletion of band q12.2 in chromosome 13 (46,XX,del(13Xq12.2)). This is the second report concerning involvement of chromosome 13q and Moebius syndrome. The observation raises the possibility that a gene responsible for Moebius syndrome is located in this region of chromosome 13. Moebius syndrome (MS) consists of congenital facial...

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ژورنال

عنوان ژورنال: Developmental Medicine & Child Neurology

سال: 2019

ISSN: 0012-1622,1469-8749

DOI: 10.1111/dmcn.14379